National Security Presidential Memorandum-33 (NSPM-33): Presidential Memorandum on U.S. Government-Supported Research and Development National Security Policy

White House OSTP / NSTC Research Security Subcommittee|Presidential Memorandum

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Summary

A Presidential Memorandum issued in January 2021 to strengthen protections of U.S. Government-supported R&D against foreign government interference and exploitation. It focuses on ensuring full disclosure of potential conflicts of interest and commitment by recipients of federal R&D and requires research institutions receiving over $50 million in federal R&D funding to certify they operate a research security program covering cybersecurity, foreign travel security, insider threat awareness, and export control training. As of November 2025, federal agencies continue to coordinate and work to implement this requirement for awardee institutions.

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Key Dates

Date Issued: January 1, 2021

Topics

Disclosure Requirements Research Security Programs Risk Assessment & Mitigation Training & Certification Cybersecurity Export Controls Foreign Talent Recruitment Programs

Relevant Roles

Principal Investigator / Senior Key PersonnelSponsored Programs / Pre-Award StaffResearch Security Officer / Export ControlInstitutional LeadershipIT / Cybersecurity Staff

Sub-items

Recommended Practices for Strengthening the Security and Integrity of America's Science and Technology Research Enterprise

NSTC Research Security Subcommittee|Jan 1, 2021

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A supplement to NSPM-33 outlining recommendations for research organizations to enhance research security and integrity. Categories include: Demonstrate organizational leadership and oversight; Establish an expectation of openness and transparency; Provide and share training, support, and information; Ensure effective mechanisms for compliance with organizational policies; and Manage potential risks associated with collaborations and data.

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Guidance for Implementing NSPM-33

White House OSTP / NSTC Research Security Subcommittee|Jan 1, 2022

SupersededFederal

A January 2022 report by the White House OSTP/NSTC Research Security Subcommittee providing additional details on 1.) Disclosure Requirements and Standardization 2.) Persistent Identifiers 3.) Consequences for Violation of Disclosure Requirements 4.) Information Sharing and 5.) Research Security Programs. Largely superseded by the final July 9, 2024 guidelines.